Jamalpur Science & Technology University is established on 28 November 2017 vide act no 24 of 2017 as the 44th public university of Bangladesh. The Honorable Chancellor of the University and President of the People’s Republic of Bangladesh appointed Professor Dr. Mohammad Raknuzzaman as the 3rd Vice Chancellor. He joined as the Vice Chancellor of Jamalpur Science and Technology University on 22 October 2024. Although a new university yet under the dynamic leadership of the Vice Chancellor, the university has achieved remarkable milestones not only in academic, administrative and financial activities also in observing various national days and sports and cultural activities. The university authority has already planned to construct infrastructure for secured campus with modern educational facilities and high standard research environment surrounded by natural beauty. In 1998, Mirza Azam, member of parliament for the Jamalpur-3 constituency, established Sheikh Fazilatunnecha Mujib Fisheries College on 33 acres in Melandaha Upazila of Jamalpur District. Classes began there in 2000. Azam lobbied for the college to be upgraded to a public university. On 30 January 2017, the Bangladesh government agreed in principle to acquire the college and convert it into Bangamata Sheikh Fojilatunnesa Mujib Science & Technology University. "Bangamata Sheikh Fojilatunnesa Mujib Science & Technology University Bill-2017" was passed by parliament on 20 November 2017. The university was gazetted on 28 November 2017. On 19 November 2018, President Abdul Hamid appointed Syed Samsuddin Ahmed as the first vice chancellor of BSFMSTU. Initially, 136 students enrolled in four subjects: mathematics, management, social work, and engineering. The first academic session began in April 2019. Initially, the university operated from a rented building of Bangabandhu Ideal College in Jamalpur. In its second academic year, the university opened a department of electrical and electronic engineering. The university shifted to its permanent campus in January 2021. On 1 November 2022, teachers went on strike demanding the sacking of Vice Chancellor Ahmed on grounds of corruption and nepotism, charges he denied. Ahmed's term expired on 18 November. On 12 December, Md. Kamrul Alam Khan was appointed as vice chancellor.